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Practitioners
Patients
- Genotyping
State-of-the-art genotyping services - Pharmacogenetics
Personalised approach to prescribing medications - Metagenomic Sequencing
Profiling of gut, oral and vaginal microbiome - Bloodborne Infection Screening
Detection of key blood-borne infections. - Contract Research
Tailored solutions support for the entire assay lifecycle
Pharmacogenomics Testing
Practice Areas We Serve
Mental Health
For conditions including depression, anxiety, bipolar disorder, and schizophrenia
RA & Autoimmune
For inflammatory conditions including rheumatoid arthritis, lupus, and psoriatic arthritis
What is Pharmacogenomics?
Pharmacogenomics is the study of how an individual's genetic makeup affects their response to medications. By analysing specific genetic variants, pharmacogenomic testing can predict drug metabolism, efficacy, and the risk of adverse reactions (ADRs). This personalised approach to prescribing medications can significantly improve patient outcomes and reduce the trial-and-error process often associated with finding the right medication and dosage.
Quick facts:
| £2Bn | Cost to the NHS of ADRs * |
| 33% | ADRs can be reduced through pharmacogenomic testing ** |
| 30% | Patients find Clopidogrel ineffective for stroke and heart attack prevention *** |
AttoDiagnostics Pharmacogenomic Testing Services
The Pharmacogenomic Testing Service by AttoDiagnostics, covers the comprehensive testing of 120 genetic markers encoding Drug Metabolism Enzymes (DMEs) and associated transport proteins including Cytochrome P450, DPYD, COMT, Factor 2 G20210A (rs1799963), Factor V R506Q Leiden mutation (rs6025), MTHFR, TPMT, VKORC1, APOE, SLC01B1.
Our panel provides medication and treatment guidelines based on your genetics across various therapeutic areas including Psychiatry (mental health), Cardiovascular, Contraceptives, Neurology, Oncology, Pain Management, Rheumatology, Gastroenterology and others.
New genes and markers are added as and when clinically actionable evidence becomes available from the Clinical Pharmacogenetics Implementation Consortium (CPIC), Dutch Pharmacogenetics Working Group (DPWG) and the Food and Drug Administration (FDA).
PGx for Mental Health and Neurological Conditions
Tailored testing for antidepressants, antipsychotics, anxiolytics, psychostimulants, psycholeptics and psychoanaleptics, antiepileptics, and other psychiatric medications to optimise treatment for conditions such as depression, anxiety, bipolar disorder, and schizophrenia.
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Example Medications
PGx for Cardiovascular Conditions
Analysis of genetic variants affecting the response to medications used in treating hypertension and other cardiovascular conditions. (Beta blocking agents, lipid modifying agents, antiarrhythmics and antihypertensives).
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Example Medications
PGx for Contraceptives and Hormone Replacement Therapy
Genetic testing to identify the risk of venous thromboembolism during sex hormone and contraceptive therapy. Our analysis supports Genitourinary Medicine (GUM) practitioners and covers topical and systemic use of contraceptives, estrogens, progestogens and antiandrogens.
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Example Medications
How to Access Our Services
Effective PGx testing strategies typically include the following steps:
- Consultation
- Sample Collection
- Analysis and Reporting
- Ongoing Support
Brands and healthcare providers can consult with our expert team to determine the most appropriate pharmacogenomics test for their patients or clients.
We provide easy-to-use kits for collecting buccal swab samples, ensuring a non-invasive and convenient testing process. These can be branded for your organisation.
Our advanced testing laboratory analyses the genetic profile and can deliver raw data or an unbranded report.
We offer continuous support to our customers helping them interpret the results and integrate pharmacogenomic insights into clinical operation, helping advance the state of precision healthcare.
